β-Arrestin-Mediated Signaling Improves the Efficacy of Therapeutics
β-Arrestins (β-arrestin-1 and β-arrestin-2) were first identified as proteins that have the ability to desensitize G protein-coupled receptors (GPCRs). However, it has recently been found that β-arrestins can activate signaling pathways independent of G protein activation. The diversity of these sig...
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| Format: | Book |
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Elsevier,
2012-01-01T00:00:00Z.
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