No association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear families

• Main Authors: Yue Hua (Author), Zhang Hao (Author), He Jin-Wei (Author), Gao Gao (Author), Zhang Zhen-Lin (Author), Hu Wei-Wei (Author), Gu Jie-Mei (Author), Fu Wen-Zhen (Author), Hu Yun-Qiu (Author), Li Miao (Author), Liu Yu-Juan (Author), Yu Jin-Bo (Author)
• Format: Bog
• Udgivet: BMC, 2010-01-01T00:00:00Z.
• Fag: article
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<p>Abstract</p> <p>Background</p> <p>The Wnt/beta-catenin signaling pathway plays an important role in skeletal development. Polymorphisms of frizzled-related protein (FRZB), an antagonist of this pathway, may generate variations in bone mineral density (BMD). In this s...