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A Monocarbonyl Curcuminoid Derivative Inhibits the Activity of Human Glutathione Transferase A4-4 and Chemosensitizes Glioblastoma Cells to Temozolomide

Human glutathione transferase A4-4 (hGSTA4-4) displays high catalytic efficiency towards 4-hydroxyalkenals and other cytotoxic and mutagenic products of radical reactions and lipid peroxidation. Its role as a target for the chemosensitization of cancer cells has not been investigated so far. In this...

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Main Authors: Steliana Tsouri (Author), Evanthia Tselo (Author), Georgios E. Premetis (Author), Veronika Furlan (Author), Panagiota D. Pantiora (Author), Barbara Mavroidi (Author), Dimitris Matiadis (Author), Maria Pelecanou (Author), Anastassios C. Papageorgiou (Author), Urban Bren (Author), Marina Sagnou (Author), Nikolaos E. Labrou (Author)
Format: Book
Published: MDPI AG, 2024-03-01T00:00:00Z.
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