Cover Image

Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Inhibiting Ferroptosis Signaling Pathway

Silicosis is a fatal occupational lung disease which currently has no effective treatment. Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-inflammatory, anti-oxidant and anti-cancer bioactivity. However, whether DHQ protects against silica-induced lung fibrosis remains unknown. The...

Full description

Saved in:

Bibliographic Details
Main Authors:	Leyong Yuan (Author), Yan Sun (Author), Ning Zhou (Author), Weipeng Wu (Author), Weidong Zheng (Author), Yukun Wang (Author)
Format:	Book
Published:	Frontiers Media S.A., 2022-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis
by: Meiyue Song, et al.
Published: (2022)

Metformin Attenuates Silica-Induced Pulmonary Fibrosis by Activating Autophagy via the AMPK-mTOR Signaling Pathway
by: Shu-xian Li, et al.
Published: (2021)

Dihydroquercetin Activates AMPK/Nrf2/HO-1 Signaling in Macrophages and Attenuates Inflammation in LPS-Induced Endotoxemic Mice
by: Liming Lei, et al.
Published: (2020)

Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway
by: Xiaohe Li, et al.
Published: (2021)

Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2
by: Yanfang Peng, et al.
Published: (2021)

Feifukang ameliorates pulmonary fibrosis by inhibiting JAK-STAT signaling pathway
by: Hongbo Li, et al.
Published: (2018)

Dihydroquercetin ameliorates LPS-induced neuroinflammation and memory deficit
by: Qadir Alam, et al.
Published: (2022)

Quercetin Alleviates Pulmonary Fibrosis in Mice Exposed to Silica by Inhibiting Macrophage Senescence
by: Fei Geng, et al.
Published: (2022)

Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling
by: Xin Wang, et al.
Published: (2021)

Preparation, characterization, and biological activity of the inclusion complex of dihydroquercetin and β-Cyclodextrin
by: Yaping Xu, et al.
Published: (2023)

Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling
by: Shashi Bala, et al.
Published: (2023)

Liposome-trimethyl chitosan nanoparticles codeliver insulin and siVEGF to treat corneal alkali burns by inhibiting ferroptosis
by: Xiaojing Xiong, et al.
Published: (2023)

Doxofylline ameliorates liver fibrosis by regulating the ferroptosis signaling pathway
by: Lenan Xu, et al.
Published: (2023)

Targeting Ferroptosis Attenuates Interstitial Inflammation and Kidney Fibrosis
by: Lu Zhou, et al.
Published: (2021)

Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice
by: Jizhen Huang, et al.
Published: (2020)

Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGF-β1/Smad Signaling Pathway
by: Yali Li, et al.
Published: (2022)

Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition
by: Sun Young Kyung, et al.
Published: (2018)

Gypenosides Attenuate Pulmonary Fibrosis by Inhibiting the AKT/mTOR/c-Myc Pathway
by: Suqing Liu, et al.
Published: (2022)

Dihydromyricetin Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting SPHK1/mTOR Signaling and Targeting Ferroptosis
by: Xie J, et al.
Published: (2022)

Inhibition of FGFR2 Signaling by Cynaroside Attenuates Liver Fibrosis
by: Qilin Meng, et al.
Published: (2023)

miR-135a Alleviates Silica-Induced Pulmonary Fibrosis by Targeting NF-κB/Inflammatory Signaling Pathway
by: Bin Xie, et al.
Published: (2020)

Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
by: Guiyun Wang, et al.
Published: (2024)

Magnolol Attenuates Right Ventricular Hypertrophy and Fibrosis in Hypoxia-Induced Pulmonary Arterial Hypertensive Rats Through Inhibition of the JAK2/STAT3 Signaling Pathway
by: Minyi Fu, et al.
Published: (2021)

Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway
by: Jin-yu Yang, et al.
Published: (2019)

Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways
by: Jin F, et al.
Published: (2021)

Nephropathy 1st inhibits renal fibrosis by activating the PPARγ signaling pathway
by: Linjie Mu, et al.
Published: (2022)

Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2
by: Xiang Tong, et al.
Published: (2021)

Isoliquiritigenin Attenuates UUO-Induced Renal Inflammation and Fibrosis by Inhibiting Mincle/Syk/NF-Kappa B Signaling Pathway
by: Liao Y, et al.
Published: (2020)

Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation
by: Danlei Li, et al.
Published: (2022)

Molecular mechanisms of ferroptosis and the potential therapeutic targets of ferroptosis signaling pathways for glioblastoma
by: Meng Zhang, et al.
Published: (2022)

Effects of Nervilia fordii Extract on Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway
by: Yufeng Yao, et al.
Published: (2021)

Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway
by: Zhuanghua Liu, et al.
Published: (2022)

Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway
by: Qian Zeng, et al.
Published: (2024)

Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling
by: Zhang L, et al.
Published: (2015)

Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway
by: Jiang Li, et al.
Published: (2023)

Raltegravir Attenuates Experimental Pulmonary Fibrosis In Vitro and In Vivo
by: Xue Zhang, et al.
Published: (2019)

Galangin Attenuates Myocardial Ischemic Reperfusion-Induced Ferroptosis by Targeting Nrf2/Gpx4 Signaling Pathway
by: Yang T, et al.
Published: (2023)

Over-Expression of Inhibitor of Differentiation 2 Attenuates Post-Infarct Cardiac Fibrosis Through Inhibition of TGF-β1/Smad3/HIF-1α/IL-11 Signaling Pathway
by: Lin Yin, et al.
Published: (2019)

Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis
by: MingShan Zhang, et al.
Published: (2024)

Elamipretide(SS-31) Attenuates Idiopathic Pulmonary Fibrosis by Inhibiting the Nrf2-Dependent NLRP3 Inflammasome in Macrophages
by: Yunjuan Nie, et al.
Published: (2023)