A novel human monoclonal antibody specific to the A33 glycoprotein recognizes colorectal cancer and inhibits metastasis

• Huvudupphovsmän: Patrizia Murer (Författare, medförfattare), Louis Plüss (Författare, medförfattare), Dario Neri (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Colorectal cancer represents the second most common cause of cancer-related death. The human A33 transmembrane glycoprotein is a validated tumor-associated antigen, expressed in 95% of primary and metastatic colorectal cancers. Using phage display technology, we generated a human monoclonal antibody...