Exuberant case of verrucous cutaneous leishmaniasis

Abstract Cutaneous leishmaniasis represents a public health problem that affects 85 countries. It is an endemic disease in Brazil, having an important socioeconomic impact. An exuberant case of cutaneous leishmaniasis is reported herein. A 28-year-old male patient with Down syndrome had had verrucou...

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Main Authors: Jana Regis Novaes (Author), Luise Ribeiro Daltro (Author), Thiago Amparo Ferreira (Author), Paulo Roberto Lima Machado (Author)
Format: Book
Published: Sociedade Brasileira de Dermatologia, 2022-02-01T00:00:00Z.
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Summary:Abstract Cutaneous leishmaniasis represents a public health problem that affects 85 countries. It is an endemic disease in Brazil, having an important socioeconomic impact. An exuberant case of cutaneous leishmaniasis is reported herein. A 28-year-old male patient with Down syndrome had had verrucous plaques on the back for over a year, with progressive growth. PCR of a lesion sample was positive for Leishmania braziliensis. The patient's condition was classified as atypical cutaneous leishmaniasis. He was successfully treated with amphotericin B and miltefosine. The treatment remains a challenge, given the toxicity and low cure rate of the currently recommended drugs.
Item Description:0365-0596
10.1016/j.abd.2020.11.011