Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor

Inhibition of histone deacetylases (HDACs) has been an important emerging therapy for the treatment of multiple cancers. However, the application of HDAC inhibitors is restricted by the limited potency against solid tumors. In order to discover novel HDAC inhibitors with potent antitumor activities,...

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Main Authors: Lihui Zhang (Author), Xiaoyang Li (Author), Yiming Chen (Author), Minghui Wan (Author), Qixiao Jiang (Author), Li Zhang (Author), C. James Chou (Author), Weiguo Song (Author), Lei Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
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