High-Throughput Drug Stability Assessment via Biomimetic Metalloporphyrin-Catalyzed Reactions Using Laser-Assisted Rapid Evaporative Ionization Mass Spectrometry (LA-REIMS)

• Main Authors: András Marton (Author), Zsombor Mohácsi (Author), Balázs Decsi (Author), Balázs Csillag (Author), Júlia Balog (Author), Richard Schäffer (Author), Tamás Karancsi (Author), György Tibor Balogh (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background:</b> Building extensive drug candidate libraries as early in the development pipeline as possible, with high-throughput in vitro absorption, distribution, metabolism, and excretion (ADME) profiling, is crucial for the selection of lead compounds to guide subsequent research...