The ectodomains of the lymphocyte scavenger receptors CD5 and CD6 interact with tegumental antigens from Echinococcus granulosus sensu lato and protect mice against secondary cystic echinococcosis.

• Main Authors: Gustavo Mourglia-Ettlin (Author), Sebastián Miles (Author), María Velasco- (Author), Noelia Armiger-Borràs (Author), Marcela Cucher (Author), Sylvia Dematteis (Author), Francisco Lozano (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Scavenger Receptors (SRs) from the host's innate immune system are known to bind multiple ligands to promote the removal of non-self or altered-self targets. CD5 and CD6 are two highly homologous class I SRs mainly expressed on all T cells and the B1a cell subset,...