Site-Specific Antibody Conjugation to Engineered Double Cysteine Residues
Site-specific antibody conjugations generate homogeneous antibody-drug conjugates with high therapeutic index. However, there are limited examples for producing the site-specific conjugates with a drug-to-antibody ratio (DAR) greater than two, especially using engineered cysteines. Based on availabl...
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Main Authors: | Qun Zhou (Author), Josephine Kyazike (Author), Ekaterina Boudanova (Author), Michael Drzyzga (Author), Denise Honey (Author), Robert Cost (Author), Lihui Hou (Author), Francis Duffieux (Author), Marie-Priscille Brun (Author), Anna Park (Author), Huawei Qiu (Author) |
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Format: | Book |
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MDPI AG,
2021-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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