Epidemiological, clinical and imaging profile of Multiple Sclerosis

<p><strong>Background:</strong> multiple sclerosis is a neurological, autoimmune, degenerative, chronic and progressive demyelinating disease associated with different genetic and environmental factors.<br /><strong>Objective:</strong> to characterize epidemiologi...

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Autori principali: Làzaro Aurelio Vàzquez Gòmez (Autore), Carlos Hidalgo Mesa (Autore), Benita Mabel Beltrán González (Autore), Yunier Broche Pérez (Autore), Ana María Mederos Herrera (Autore)
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Pubblicazione: Centro Provincial de Información de Ciencias Médicas. Cienfuegos, 2021-12-01T00:00:00Z.
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Riassunto:<p><strong>Background:</strong> multiple sclerosis is a neurological, autoimmune, degenerative, chronic and progressive demyelinating disease associated with different genetic and environmental factors.<br /><strong>Objective:</strong> to characterize epidemiologically, clinically and imaging patients with a diagnosis of multiple sclerosis.<br /><strong>Methods:</strong> observational, descriptive, cross-sectional study on all patients with a diagnosis of multiple sclerosis with follow-up at the Arnaldo Milián Castro Provincial University Clinical-Surgical Hospital, in Villa Clara during the period from January 2014 to December 2019. The epidemiological variables analyzed: sex, age of disease onset, skin color, place of origin; clinical variables: symptoms at the beginning and at present; number of shoots; years of evolution, clinical forms; Imaging variables: number of lesions, location, atrophy or change in signal intensity of the corpus callosum and McDonald's criterion fulfilled.<br /><strong>Results:</strong> there was a higher incidence of females with 80 patients. It was found that 59 patients had a relapsing-remitting clinical form, 21 patients had a secondary progressive form, 4 patients had a primary progressive and 2 patients had a relapsing progressive one. Symptoms: motor deficit, sensory deficit and cerebellar alterations were the most frequent at the beginning and at present. Disability evaluated as minimal was found in 50 patients and 31 patients had 2 to 4 lesions on nuclear magnetic resonance.<br /><strong>Conclusions:</strong> Adequate epidemiological information on patients with multiple sclerosis in Villa Clara was obtained satisfactorily. It is important to consider this report as a basis for decision-making on issues of projection of treatment and care, aspects of great importance in high-cost diseases, such as multiple sclerosis.</p>
Descrizione del documento:1727-897X