The Different Strategies for the Radiolabeling of [²¹¹At]-Astatinated Radiopharmaceuticals

• Main Authors: Jie Gao (Author), Mei Li (Author), Jingjing Yin (Author), Mengya Liu (Author), Hongliang Wang (Author), Jin Du (Author), Jianguo Li (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Astatine-211 (²¹¹At) has emerged as a promising radionuclide for targeted alpha therapy of cancer by virtue of its favorable nuclear properties. However, the limited in vivo stability of ²¹¹At-labeled radiopharmaceuticals remains a major challenge. This...