A study to compare maternal and perinatal outcome in early vs. late onset preeclampsia

ObjectiveThe risk factors, clinical trends, and maternal and fetal health of early- and late-onset preeclampsia have not been adequately studied. We examined the effects of early- and late-onset preeclampsia on maternal and perinatal outcomes as well as the known risk factors of preeclampsia.Methods...

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Main Authors: Pooja Wadhwani (Author), Pradip Kumar Saha (Author), Jaswinder Kaur Kalra (Author), Shalini Gainder (Author), Venkataseshan Sundaram (Author)
Format: Book
Published: Korean Society of Obstetrics and Gynecology, 2020-05-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Pooja Wadhwani  |e author 
700 1 0 |a Pradip Kumar Saha  |e author 
700 1 0 |a Jaswinder Kaur Kalra  |e author 
700 1 0 |a Shalini Gainder  |e author 
700 1 0 |a Venkataseshan Sundaram  |e author 
245 0 0 |a A study to compare maternal and perinatal outcome in early vs. late onset preeclampsia 
260 |b Korean Society of Obstetrics and Gynecology,   |c 2020-05-01T00:00:00Z. 
500 |a 2287-8572 
500 |a 2287-8580 
500 |a 10.5468/ogs.2020.63.3.270 
520 |a ObjectiveThe risk factors, clinical trends, and maternal and fetal health of early- and late-onset preeclampsia have not been adequately studied. We examined the effects of early- and late-onset preeclampsia on maternal and perinatal outcomes as well as the known risk factors of preeclampsia.MethodsOne hundred and fifty women with preeclampsia were consecutively enrolled in each group. Those who developed preeclampsia before 34 weeks of gestation were identified as having early-onset preeclampsia, while those who developed at 34 weeks or later were identified as having late-onset preeclampsia. Maternal and perinatal outcomes were compared between groups.ResultsCompared with the late-onset group, the early-onset group had higher rates of abruptio placentae (16% vs. 7.3%; P=0.019), but there was no intergroup difference in the composite maternal outcomes. A significantly higher number of women with early-onset preeclampsia developed severe features during the disease course, and most required treatment with antihypertensive drugs. Late-onset preeclampsia was more prevalent among primigravid mothers. Babies born to mothers with early-onset preeclampsia had a significantly higher rate of adverse outcomes.ConclusionThese study findings indicate that women with early-onset preeclampsia had more adverse outcome than those with late-onset preeclampsia, but the difference was not statistically significant. There were more babies with adverse perinatal outcomes in the early-than late-onset group. 
546 |a EN 
546 |a KO 
690 |a early-onset preeclampsia 
690 |a late onset preeclampsia 
690 |a maternal outcome 
690 |a perinatal outcome 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Obstetrics & Gynecology Science, Vol 63, Iss 3, Pp 270-277 (2020) 
787 0 |n http://ogscience.org/upload/pdf/ogs-63-270.pdf 
787 0 |n https://doaj.org/toc/2287-8572 
787 0 |n https://doaj.org/toc/2287-8580 
856 4 1 |u https://doaj.org/article/1d5e711d543f40a5b18a7cd8cfa6c34c  |z Connect to this object online.