Cardiovascular and renal effects of hyperuricaemia and gout

A number of epidemiological studies have reported an association between serum uric acid levels and a wide variety of high-risk conditions including hypertension, insulin resistance, and kidney and cerebro-cardiovascular disease. All things considered, serum uric acid may induce cardiovascular and k...

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Bibliographic Details
Main Authors: R. Pontremoli (Author), G. Leoncini (Author), F. Viazzi (Author)
Format: Book
Published: PAGEPress Publications, 2012-01-01T00:00:00Z.
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Summary:A number of epidemiological studies have reported an association between serum uric acid levels and a wide variety of high-risk conditions including hypertension, insulin resistance, and kidney and cerebro-cardiovascular disease. All things considered, serum uric acid may induce cardiovascular and kidney events both directly and indirectly by promoting other well-known mechanisms of damage. While asymptomatic hyperuricemia is currently not considered to be an indication for urate lowering therapy, there is growing evidence indicating a linear relationship between pharmacological reduction in serum uric acid and incidence of cardiovascular and renal events.
Item Description:10.4081/reumatismo.2011.253
0048-7449
2240-2683