Development of Lomustine and <i>n</i>-Propyl Gallate Co-Encapsulated Liposomes for Targeting Glioblastoma Multiforme via Intranasal Administration

• Main Authors: Gábor Katona (Author), Fakhara Sabir (Author), Bence Sipos (Author), Muhammad Naveed (Author), Zsuzsanna Schelz (Author), István Zupkó (Author), Ildikó Csóka (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

This work aimed to develop lomustine (LOM) and <i>n</i>-propyl gallate (PG)-loaded liposomes suitable for targeting glioblastoma multiforme (GBM) via the auspicious nose-to-brain drug delivery pathway. The therapeutical effect of LOM, as a nitrosourea compound, can be potentiated by PG s...