Cold urticaria: A clue to a silent systemic disease

• Main Authors: Joana Rodrigues Sarmento Branco (Author), Sara Completo Marques (Author), Piedade Sande Lemos (Author), Anna Sokolova (Author)
• Format: Book
• Published: Sociedade Portuguesa de Dermatologia e Venereologia, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A previously healthy 2-year-old boy with a history of recurrent hives after exposure to cold air. A diagnosis of cold-induced urticaria was confirmed by a positive ice cube test but in the investigation, we found hepatic cytolysis and a lack of alpha-1-protein band level in protein electrophoresis....