Keratolysis exfoliativa-like eruption induced by ranolazione

Dermatoses affecting palms may represent a dermatologic challenge from both the diagnostic, and therapeutic point of view. Patients with supposedly occupational dermatitis can spend months or even years in a frustrating attempt to avoid contact with possible irritants or allergens. To underline the...

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Bibliographic Details
Main Authors: Elena Pierobon (Author), Lerica Germi (Author), Andrea Sechi (Author), Giampaolo Trevisan (Author), Elena Pezzolo (Author), Claudio Feliciani (Author), Luigi Naldi (Author)
Format: Book
Published: PAGEPress Publications, 2021-10-01T00:00:00Z.
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Summary:Dermatoses affecting palms may represent a dermatologic challenge from both the diagnostic, and therapeutic point of view. Patients with supposedly occupational dermatitis can spend months or even years in a frustrating attempt to avoid contact with possible irritants or allergens. To underline the importance of a thorough unbiased analysis of the patient's history and clinical features, we present the iconic case of a bricklayer affected by a chronic, disabling desquamation of palms which in the end was classified as keratolysis exfoliativa (KE) attributed to ranolazine-intake, an antianginal drug. To the best of our knowledge, this specific adverse effect of drug-induced KE of palms has never been reported before in association with ranolazine.
Item Description:10.4081/dr.2021.9264
2036-7392
2036-7406