The Phenoxyphenol Compound diTFPP Mediates Exogenous C₂-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells

• Main Authors: Wen-Tsan Chang (Author), Yung-Ding Bow (Author), Yen-Chun Chen (Author), Chia-Yang Li (Author), Jeff Yi-Fu Chen (Author), Yi-Ching Chu (Author), Yen-Ni Teng (Author), Ruei-Nian Li (Author), Chien-Chih Chiu (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma (HCC) is a severe disease that accounts for 80% of liver cancers. Chemotherapy is the primary therapeutic strategy for patients who cannot be treated with surgery or who have late-stage HCC. C₂-ceramide is an effective reagent that has been found to in...