Dysregulation of Mesenchymal Cell Survival Pathways in Severe Fibrotic Lung Disease: The Effect of Nintedanib Therapy
Impaired apoptotic clearance of myofibroblasts can result in the continuous expansion of scar tissue during the persistent injury in the lung. However, the molecular and cellular mechanisms underlying the apoptotic clearance of multiple mesenchymal cells including fibrocytes, fibroblasts and myofibr...
Saved in:
Main Authors: | Rajesh K. Kasam (Author), Geereddy B. Reddy (Author), Anil G. Jegga (Author), Satish K. Madala (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2019-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway
by: Afshin Ebrahimpour, et al.
Published: (2021) -
Why medical students do not like to join rural health service? An exploratory study in India
by: Srinivas Nallala, et al.
Published: (2015) -
Changing Trends in Computational Drug Repositioning
by: Jaswanth K. Yella, et al.
Published: (2018) -
Clinical development of nintedanib for advanced non-small-cell lung cancer
by: Takeda M, et al.
Published: (2015) -
Evaluation of Pirfenidone and Nintedanib in a Human Lung Model of Fibrogenesis
by: KM Roach, et al.
Published: (2021)