Macrophage membrane- and cRGD-functionalized thermosensitive liposomes combined with CPP to realize precise siRNA delivery into tumor cells

• Main Authors: Jingxue Nai (Author), Jinbang Zhang (Author), Jiaxin Li (Author), Hui Li (Author), Yang Yang (Author), Meiyan Yang (Author), Yuli Wang (Author), Wei Gong (Author), Zhiping Li (Author), Lin Li (Author), Chunsheng Gao (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the success of small interfering RNAs (siRNAs) in clinical settings, their fast clearance and poor delivery efficiency to target cells still hinder their therapeutic effect. Herein, a new treatment system was constructed by combining thermosensitive liposomes with the macrophage membrane, tu...