Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México

• Main Authors: Joel Barroso-Santos (Author), Angelina Ingrid Robledo-Martínez (Author), Sara Elva Espinosa-Padilla (Author), Rubén Genaro Hurtado del Ángel (Author), Felipe Arteaga-García (Author), Mónica Langarica-Bulos (Author), José Antonio Madrid- (Author), Beatriz Adriana Sánchez-Reyes (Author), Sarai Eunice Hernández-Cadena (Author), Jorge Iván Suárez-Soto (Author), Carolina Delgado-Amézquita (Author), Brenda Godínez-Hernández (Author), Octavio Otamendi-Canales (Author), Angélica Saraí Jiménez-Osorio (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 10.3390/pediatric15020030; 2036-7503
• Keywords: multisystemic inflammatory syndrome; COVID-19; children; Medicine; R; Pediatrics; RJ1-570
• Source: Pediatric Reports, Vol 15, Iss 2, Pp 341-348 (2023)

Multisystemic inflammatory syndrome (MIS-C) is an inflammatory condition temporally associated with COVID-19 in children; nevertheless, the clinical and immunologic spectrum of MIS-C is heterogeneous, and its long-term effects are unknown. During the period of August 2020 to December 2021, a total of 52 MIS-C cases were confirmed in pediatric patients from the Hospital del Niño DIF Hidalgo, diagnosed using criteria from the World Health Organization. All patients had serologic IgG confirmation of SARS-CoV2, the mean age of the patients was 7 years, and 94% of the patients did not have a previous underlying disease. In addition to the presentation of lymphopenia, neutropenia, and thrombocytopenia, elevations in D-dimer and ferritin levels were observed in all patients. There was clinical improvement with intravenous gamma globulin and corticosteroid treatment.