Cover Image

Dopamine and Citicoline-Co-Loaded Solid Lipid Nanoparticles as Multifunctional Nanomedicines for Parkinson's Disease Treatment by Intranasal Administration

This work aimed to evaluate the potential of the nanosystems constituted by dopamine (DA) and the antioxidant Citicoline (CIT) co-loaded in solid lipid nanoparticles (SLNs) for intranasal administration in the treatment of Parkinson disease (PD). Such nanosystems, denoted as DA-CIT-SLNs, were design...

Full description

Saved in:

Bibliographic Details
Main Authors:	Stefano Castellani (Author), Giorgia Natalia Iaconisi (Author), Francesca Tripaldi (Author), Vito Porcelli (Author), Adriana Trapani (Author), Eugenia Messina (Author), Lorenzo Guerra (Author), Cinzia Di Franco (Author), Giuseppe Maruccio (Author), Anna Grazia Monteduro (Author), Filomena Corbo (Author), Sante Di Gioia (Author), Giuseppe Trapani (Author), Massimo Conese (Author)
Format:	Book
Published:	MDPI AG, 2024-08-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Novel Nanoparticles Based on <i>N</i>,<i>O</i>-Carboxymethyl Chitosan-Dopamine Amide Conjugate for Nose-to-Brain Delivery
by: Adriana Trapani, et al.
Published: (2022)

The Encapsulation of Citicoline within Solid Lipid Nanoparticles Enhances Its Capability to Counteract the 6-Hydroxydopamine-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells
by: Andrea Margari, et al.
Published: (2022)

Polyethylenimine-mediated gene delivery to the lung and therapeutic applications
by: Sante Di Gioia, et al.
Published: (2008)

Combined Dopamine and Grape Seed Extract-Loaded Solid Lipid Nanoparticles: Nasal Mucosa Permeation, and Uptake by Olfactory Ensheathing Cells and Neuronal SH-SY5Y Cells
by: Adriana Trapani, et al.
Published: (2023)

Choosing Wisely in pediatric healthcare: A narrative review
by: Sandra Trapani, et al.
Published: (2023)

Corrigendum: Choosing wisely in pediatric healthcare: a narrative review
by: Sandra Trapani, et al.
Published: (2024)

The Potential Neuroprotective Role of Citicoline in Hepatic Encephalopathy
by: Farshad O, et al.
Published: (2020)

Role of Citicoline in the Management of Traumatic Brain Injury
by: Julio J. Secades
Published: (2021)

When the limp has a dietary cause: A retrospective study on scurvy in a tertiary Italian pediatric hospital
by: Daniela Masci, et al.
Published: (2022)

Citicoline in Vascular Cognitive Impairment: Some Latest Evidences
by: Pietro Gareri, et al.
Published: (2017)

Citicoline: A Candidate for Adjunct Treatment of Multiple Sclerosis
by: Paweł Grieb, et al.
Published: (2021)

Citicoline in Ophthalmological Neurodegenerative Disease: A Comprehensive Review
by: Francesco Oddone, et al.
Published: (2021)

A Micellar-Hydrogel Nanogrid from a UV Crosslinked Inulin Derivative for the Simultaneous Delivery of Hydrophobic and Hydrophilic Drugs
by: Delia Mandracchia, et al.
Published: (2018)

Recent progress of hypoxia-modulated multifunctional nanomedicines to enhance photodynamic therapy: opportunities, challenges, and future development
by: Yixin Sun, et al.
Published: (2020)

An uncommon "third window" in retrofenestral otosclerosis
by: Zambonini Giulia, et al.
Published: (2022)

Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain
by: Giuseppe Di Giovanni, et al.
Published: (2020)

Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson's disease
by: Shengnan Tang, et al.
Published: (2019)

Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells
by: Annalucia Carbone, et al.
Published: (2018)

Diagnosis and treatment of vascular cognitive impairment, the use of citicoline: A review
by: Vladimir A. Parfenov
Published: (2024)

Current knowledge on the neuroprotective and neuroregenerative properties of citicoline in acute ischemic stroke
by: Martynov MY, et al.
Published: (2015)

Citicoline in hypoxic ischemic encephalopathy in neonates: a randomized controlled trial
by: Abeer Salamah, et al.
Published: (2023)

The Effect of Citicoline Injections on Children with Organic Brain Syndrome Caused by Infection
by: Endang Warsiki
Published: (2019)

Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
by: Chiara De Luca, et al.
Published: (2010)

Thromboembolic complications in children with COVID-19 and MIS-C: A narrative review
by: Sandra Trapani, et al.
Published: (2022)

Musculoskeletal infections in childhood: Recognize early to quickly and properly treat
by: Sandra Trapani
Published: (2024)

The dopamine system: insights between kidney and brain
by: Antonio de Donato, et al.
Published: (2022)

In vivo study of pharmacokinetic parameters of a new combination drug based on citicoline and memantine
by: Boris B. Sysuev, et al.
Published: (2021)

Development and validation of spectrophotometric methods for simultaneous estimation of citicoline and piracetam in tablet dosage form
by: Akhila Sivadas, et al.
Published: (2013)

Expanding the armory for treating lymphoma: Targeting redox cellular status through thioredoxin reductase inhibition
by: Sicong Wang, et al.
Published: (2022)

Erythema Nodosum in Children: A Narrative Review and a Practical Approach
by: Sandra Trapani, et al.
Published: (2022)

Neurological Involvement in Children with COVID-19 and MIS-C: A Retrospective Study Conducted for More than Two Years in a Pediatric Hospital
by: Giulia Abbati, et al.
Published: (2022)

Combined citicoline and docosahexaenoic acid treatment improves cognitive dysfunction following transient brain ischemia
by: Eri Nakazaki, et al.
Published: (2019)

Low-density lipoprotein nanomedicines: mechanisms of targeting, biology, and theranostic potential
by: Lin Di, et al.
Published: (2021)

Mineral medicine: from traditional drugs to multifunctional delivery systems
by: Xiaoqing Zhong, et al.
Published: (2022)

Nanomedicines
Published: (2019)

Survey on the use of Homeopathy among Pediatricians of the Italian Federation of Pediatric Physicians (FIMP) [Article in English and Italian] • [Indagine sull'utilizzo dell'Omeopatia tra i Pediatri della Federazione Italiana Medici Pediatri (FIMP)]
by: Gianfranco Trapani, et al.
Published: (2017)

Macrophage-targeted nanomedicine for the diagnosis and management of atherosclerosis
by: Ping Ping Hu, et al.
Published: (2022)

Legal Pregnancy Interruption due to Sexual Violence in a Public Hospital in the South of Brazil
by: Vitoria Finger Trapani, et al.
Published: (2023)

Pemberian Citicoline pada Tikus Cedera Saraf Mentalis: Ekspresi Gen SIRT1 Ganglion Trigeminal
by: David Pakaya, et al.
Published: (2018)

Co-Targeting of BTK and TrxR as a Therapeutic Approach to the Treatment of Lymphoma
by: Sicong Wang, et al.
Published: (2023)