Knockdown of circ-PRKCH alleviates IL-1β-treated chondrocyte cell phenotypic changes through modulating miR-502-5p/ADAMTS5 axis

• Main Authors: Zhongxing Liu (Author), Jian Cao (Author), Limin Zhang (Author), Jinlong Li (Author), Tinghan Yan (Author), Peng Zhou (Author), Sidi Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Osteoarthritis (OA) is a common joint disease characterized by progressive cartilage degradation. Circular RNAs (circRNAs) are involved in the initiation and development of OA. This study aimed to explore the potential role and mechanism of circRNA protein kinase C eta (circ-PRKCH) in OA....