CABE-RY: A PAM-flexible dual-mutation base editor for reliable modeling of multi-nucleotide variants
Multi-nucleotide variants (MNVs) represent an important type of genetic variation and have biological and clinical significance. To simulate MNVs, we designed four dual-mutation base editors combining hA3A(Y130F), TadA8e(V106W), and protospacer adjacent motif (PAM)-flexible SpRY and selected cytosin...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2021-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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