Cover Image

Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes

Objective: Storage of triglycerides in lipid droplets is governed by a set of lipid droplet-associated proteins. One of these lipid droplet-associated proteins, hypoxia-inducible lipid droplet-associated (HILPDA), was found to impair lipid droplet breakdown in macrophages and cancer cells by inhibit...

Full description

Saved in:

Bibliographic Details
Main Authors:	Montserrat A. de la Rosa Rodriguez (Author), Lei Deng (Author), Anne Gemmink (Author), Michel van Weeghel (Author), Marie Louise Aoun (Author), Christina Warnecke (Author), Rajat Singh (Author), Jan Willem Borst (Author), Sander Kersten (Author)
Format:	Book
Published:	Elsevier, 2021-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Triglyceride peroxidation progression in lipid droplets of hepatocytes in nonalcoholic steatohepatitis
by: Kota Saito, et al.
Published: (2024)

Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds
by: Lucy M. Elphick, et al.
Published: (2012)

Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes
by: Dya Fita Dibwe, et al.
Published: (2022)

Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism
by: Deepti Abbey, et al.
Published: (2021)

Pathophysiology of Lipid Droplets in Neuroglia
by: Tina Smolič, et al.
Published: (2021)

Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD
by: Douglas G. Mashek
Published: (2021)

Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox
by: Sabine Daemen, et al.
Published: (2018)

Targeting lipid droplets and lipid droplet-associated proteins: a new perspective on natural compounds against metabolic diseases
by: Xinyue Jiang, et al.
Published: (2024)

Lipid droplets control mitogenic lipid mediator production in human cancer cells
by: Eva Jarc Jovičić, et al.
Published: (2023)

Deletion of the lipid droplet protein kinase gene affects lipid droplets biogenesis, parasite infectivity, and resistance to trivalent antimony in Leishmania infantum.
by: Juliana Martins Ribeiro, et al.
Published: (2024)

Deletion of the lipid droplet protein kinase gene affects lipid droplets biogenesis, parasite infectivity, and resistance to trivalent antimony in Leishmania infantum
by: Juliana Martins Ribeiro, et al.
Published: (2024)

PGC-1α-mediated imbalance of mitochondria-lipid droplet homeostasis in neomycin-induced ototoxicity and nephrotoxicity
by: Bin Chen, et al.
Published: (2024)

Lipid droplets are formed in 2-cell-like cells
by: Asuka FURUTA, et al.
Published: (2021)

An Overview of Lipid Droplets in Cancer and Cancer Stem Cells
by: L. Tirinato, et al.
Published: (2017)

Extracellular lipids of Candida albicans biofilm induce lipid droplet formation and decreased response to a topoisomerase I inhibitor in dysplastic and neoplastic oral cells
by: Freddy Humberto MARIN-DETT, et al.
Published: (2023)

Lipid droplets in granulosa cells are correlated with reduced pregnancy rates
by: Shira Raviv, et al.
Published: (2020)

Lipid droplets synthesized during luteinization are degraded after pregnancy
by: Junichiro MITSUI, et al.
Published: (2024)

Oxidative Stress and Lipid Dysregulation in Lipid Droplets: A Connection to Chronic Kidney Disease Revealed in Human Kidney Cells
by: Zhen Chen, et al.
Published: (2022)

Lipid droplets: a candidate new research field for epithelial ovarian cancer
by: Shiro Koizume, et al.
Published: (2024)

Lipid droplet formation is spatiotemporally regulated in oocytes during follicular development in mice
by: Ryutaro AIZAWA, et al.
Published: (2023)

Oxidative Stress Induced by Lipotoxicity and Renal Hypoxia in Diabetic Kidney Disease and Possible Therapeutic Interventions: Targeting the Lipid Metabolism and Hypoxia
by: Seung Yun Chae, et al.
Published: (2023)

Case report: Diagnosis and treatment of DGAT1 deficiency-induced congenital diarrhea in two cases and literature review
by: Jian Li, et al.
Published: (2023)

Inhibition of Lipid Accumulation and Oxidation in Hepatocytes by Bioactive Bean Extracts
by: Dya Fita Dibwe, et al.
Published: (2024)

Perilipin2 depletion causes lipid droplet enlargement in the ovarian corpus luteum in mice
by: Megumi IBAYASHI, et al.
Published: (2024)

Impact of short-term high-fat feeding on lipid droplet content in mouse oocytes
by: Ryutaro AIZAWA, et al.
Published: (2020)

Supersaturation and Solubilization upon In Vitro Digestion of Fenofibrate Type I Lipid Formulations: Effect of Droplet Size, Surfactant Concentration and Lipid Type
by: Vladimir Katev, et al.
Published: (2021)

Effects of clozapine on adipokine secretions/productions and lipid droplets in 3T3-L1 adipocytes
by: Tomomi Tsubai, et al.
Published: (2017)

CHARACTERISTICS OF LIPID STORAGE DISORDERS IN CHILDREN WITH HEPATOBILIARY PATHOLOGY
by: А. E. Lavrova, et al.
Published: (2014)

Microscopy tools for the investigation of intracellular lipid storage and dynamics
by: Sabine Daemen, et al.
Published: (2016)

Effect of high NEFA concentration on lipid metabolism disorders in hepatocytes based on lipidomics
by: Xinyi Fan, et al.
Published: (2024)

Spirulina supplement and exercise training affect lipid droplets-related genes expression in visceral adipose tissue
by: Fariba Shahandeh, et al.
Published: (2024)

Perilipin 1 Deficiency Prompts Lipolysis in Lipid Droplets and Aggravates the Pathogenesis of Persistent Immune Activation in Drosophila
by: Lei Wang, et al.
Published: (2023)

DGAT1 mutations leading to delayed chronic diarrhoea: a case report
by: Luojia Xu, et al.
Published: (2020)

The Structural Integrity of the Model Lipid Membrane during Induced Lipid Peroxidation: The Role of Flavonols in the Inhibition of Lipid Peroxidation
by: Anja Sadžak, et al.
Published: (2020)

Lipid-Induced Mechanisms of Metabolic Syndrome
by: Yulia K. Denisenko, et al.
Published: (2020)

Testosterone-Induced Effects on Lipids and Inflammation
by: Stella Vodo, et al.
Published: (2013)

The formation of lipid droplets favors intracellular Mycobacterium leprae survival in SW-10, non-myelinating Schwann cells.
by: Song-Hyo Jin, et al.
Published: (2017)

Effects of β-Nicotinamide Mononucleotide, Berberine, and Cordycepin on Lipid Droplet Content and Developmental Ability of Vitrified Bovine Oocytes
by: Xi Xu, et al.
Published: (2023)

Vacuolar protein sorting 13C is a novel lipid droplet protein that inhibits lipolysis in brown adipocytes
by: Vanesa D. Ramseyer, et al.
Published: (2018)

Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway
by: Dongze Li, et al.
Published: (2022)