Insights into the Adsorption Mechanisms of the Antimicrobial Peptide CIDEM-501 on Membrane Models

• Glavni autori: Daniel Alpízar-Pedraza (Autor), Yessica Roque-Diaz (Autor), Hilda Garay-Pérez (Autor), Frank Rosenau (Autor), Ludger Ständker (Autor), Vivian Montero-Alejo (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2024-02-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

CIDEM-501 is a hybrid antimicrobial peptide rationally designed based on the structure of panusin and panulirin template peptides. The new peptide exhibits significant antibacterial activity against multidrug-resistant pathogens (MIC = 2-4 μM) while conserving no toxicity in human cell lines. We con...