Mutational profiling of micro-dissected pre-malignant lesions from archived specimens

• Main Authors: Daniela Nachmanson (Author), Joseph Steward (Author), Huazhen Yao (Author), Adam Officer (Author), Eliza Jeong (Author), Thomas J. O'Keefe (Author), Farnaz Hasteh (Author), Kristen Jepsen (Author), Gillian L. Hirst (Author), Laura J. Esserman (Author), Alexander D. Borowsky (Author), Olivier Harismendy (Author)
• Format: Book
• Published: BMC, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Systematic cancer screening has led to the increased detection of pre-malignant lesions (PMLs). The absence of reliable prognostic markers has led mostly to over treatment resulting in potentially unnecessary stress, or insufficient treatment and avoidable progression. Importantl...