Plasma metabolomic and lipidomic alterations associated with anti-tuberculosis drug-induced liver injury

• Hauptverfasser: Ming-Gui Wang (Verfasst von), Shou-Quan Wu (Verfasst von), Meng-Meng Zhang (Verfasst von), Jian-Qing He (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Schlagworte: article
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Background: Anti-tuberculosis drug-induced liver injury (ATB-DILI) is an adverse reaction with a high incidence and the greatest impact on tuberculosis treatment. However, there is a lack of effective biomarkers for the early prediction of ATB-DILI. Herein, this study uses UPLC‒MS/MS to reveal the p...