Plasma metabolomic and lipidomic alterations associated with anti-tuberculosis drug-induced liver injury

• Auteurs principaux: Ming-Gui Wang (Auteur), Shou-Quan Wu (Auteur), Meng-Meng Zhang (Auteur), Jian-Qing He (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Anti-tuberculosis drug-induced liver injury (ATB-DILI) is an adverse reaction with a high incidence and the greatest impact on tuberculosis treatment. However, there is a lack of effective biomarkers for the early prediction of ATB-DILI. Herein, this study uses UPLC‒MS/MS to reveal the p...