Plasma metabolomic and lipidomic alterations associated with anti-tuberculosis drug-induced liver injury

• Ngā kaituhi matua: Ming-Gui Wang (Author), Shou-Quan Wu (Author), Meng-Meng Zhang (Author), Jian-Qing He (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Background: Anti-tuberculosis drug-induced liver injury (ATB-DILI) is an adverse reaction with a high incidence and the greatest impact on tuberculosis treatment. However, there is a lack of effective biomarkers for the early prediction of ATB-DILI. Herein, this study uses UPLC‒MS/MS to reveal the p...