Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays.
The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an estimated 1 million new cases each year. Current treatments are toxic, expensive, difficult to administer, and resistance to them is emerging. New therapeutics are urgently needed, however, screening...
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Main Authors: | Sarah L Berry (Author), Hamza Hameed (Author), Anna Thomason (Author), Marissa L Maciej-Hulme (Author), Somaia Saif Abou-Akkada (Author), Paul Horrocks (Author), Helen P Price (Author) |
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Format: | Book |
Published: |
Public Library of Science (PLoS),
2018-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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