Malignant pleural mesothelioma in a child

Malignant pleural mesothelioma (MPM) is an aggressive malignancy that occurs extremely rarely in the pediatric population. It carries a dismal prognosis. Adult studies are often used to guide therapy in the pediatric population, as a limited number of case reports form the body of pediatric literatu...

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Bibliographic Details
Main Authors: Jed Brendan Scharf (Author), Gordon Mitchell Lees (Author), Consolato Maria Sergi (Author)
Format: Book
Published: Elsevier, 2015-10-01T00:00:00Z.
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Summary:Malignant pleural mesothelioma (MPM) is an aggressive malignancy that occurs extremely rarely in the pediatric population. It carries a dismal prognosis. Adult studies are often used to guide therapy in the pediatric population, as a limited number of case reports form the body of pediatric literature. Herein, we document the course and treatment of an 8-year old male diagnosed with MPM. The diagnosis came after he presented to his family physician with dyspnea and was found to have a large right-sided chest mass on subsequent imaging. Through an initial right pneumonectomy and subsequent chest wall excision, followed by chemotherapy with Pemetrexed and Cisplatin he remains virtually disease free today, almost 2 years following surgery.
Item Description:2213-5766
10.1016/j.epsc.2015.09.002