The Desmosomal Plaque Proteins of the Plakophilin Family

• Автори: Steffen Neuber (Автор), Mario Mühmer (Автор), Denise Wratten (Автор), Peter J. Koch (Автор), Roland Moll (Автор), Ansgar Schmidt (Автор)
• Формат: Книга
• Опубліковано: Hindawi Limited, 2010-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Three related proteins of the plakophilin family (PKP1_3) have been identified as junctional proteins that are essential for the formation and stabilization of desmosomal cell contacts. Failure of PKP expression can have fatal effects on desmosomal adhesion, leading to abnormal tissue and organ deve...