Repeated 0.2-Gy γ-Ray Irradiation Attenuates the Inflammatory Process and Endotoxin Damage Induced by Lipopolysaccharides
Endotoxin damage is an acute, multi-organ disease, the most typical symptoms of which are liver injury and inflammatory cytokine storm. Endotoxin tolerance is described as the pretreatment of lipopolysaccharides (LPS) before the toxin invasion, which is consistent with the adaptive response induced...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Book |
| Published: |
SAGE Publishing,
2019-06-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_20c6eb0df15543b08592477baf2da10c | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Suhe Dong |e author |
| 700 | 1 | 0 | |a Wen Qian |e author |
| 700 | 1 | 0 | |a Tingting Liu |e author |
| 700 | 1 | 0 | |a Hu Liu |e author |
| 700 | 1 | 0 | |a Jicong Du |e author |
| 700 | 1 | 0 | |a Hainan Zhao |e author |
| 700 | 1 | 0 | |a Fu Gao |e author |
| 700 | 1 | 0 | |a Jianming Cai |e author |
| 245 | 0 | 0 | |a Repeated 0.2-Gy γ-Ray Irradiation Attenuates the Inflammatory Process and Endotoxin Damage Induced by Lipopolysaccharides |
| 260 | |b SAGE Publishing, |c 2019-06-01T00:00:00Z. | ||
| 500 | |a 1559-3258 | ||
| 500 | |a 10.1177/1559325819836355 | ||
| 520 | |a Endotoxin damage is an acute, multi-organ disease, the most typical symptoms of which are liver injury and inflammatory cytokine storm. Endotoxin tolerance is described as the pretreatment of lipopolysaccharides (LPS) before the toxin invasion, which is consistent with the adaptive response induced by low-dose radiation (LDR). In this study, we verified that LDR could resist the endotoxin damage by suppressing the increase of inflammatory cytokines, including interleukin 6, tumor necrosis factor, and NO, to improve the survival and relieve the inflammatory cell infiltration, in which low dose of LPS performed consistently with LDR. | ||
| 546 | |a EN | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Dose-Response, Vol 17 (2019) | |
| 787 | 0 | |n https://doi.org/10.1177/1559325819836355 | |
| 787 | 0 | |n https://doaj.org/toc/1559-3258 | |
| 856 | 4 | 1 | |u https://doaj.org/article/20c6eb0df15543b08592477baf2da10c |z Connect to this object online. |