Antioxidant Activities of Alkyl Substituted Pyrazine Derivatives of Chalcones-In Vitro and In Silico Study

• Main Authors: Višnja Stepanić (Author), Mario Matijašić (Author), Tea Horvat (Author), Donatella Verbanac (Author), Marta Kučerová-Chlupáčová (Author), Luciano Saso (Author), Neven Žarković (Author)
• Format: Book
• Published: MDPI AG, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chalcones are polyphenolic secondary metabolites of plants, many of which have antioxidant activity. Herein, a set of 26 synthetic chalcone derivatives with alkyl substituted pyrazine heterocycle A and four types of the monophenolic ring B, were evaluated for the potential radical scavenging and ant...