Hydrogen sulfide prodrugs-a review
Hydrogen sulfide (H2S) is recognized as one of three gasotransmitters together with nitric oxide (NO) and carbon monoxide (CO). As a signaling molecule, H2S plays an important role in physiology and shows great potential in pharmaceutical applications. Along this line, there is a need for the develo...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Elsevier,
2015-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Hydrogen sulfide (H2S) is recognized as one of three gasotransmitters together with nitric oxide (NO) and carbon monoxide (CO). As a signaling molecule, H2S plays an important role in physiology and shows great potential in pharmaceutical applications. Along this line, there is a need for the development of H2S prodrugs for various reasons. In this review, we summarize different H2S prodrugs, their chemical properties, and some of their potential therapeutic applications. |
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| Item Description: | 2211-3835 2211-3843 10.1016/j.apsb.2015.06.004 |