Exploring the Impact of Model-Informed Precision Dosing on Procalcitonin Concentrations in Critically Ill Patients: A Secondary Analysis of the DOLPHIN Trial

• Main Authors: Sarah Dräger (Author), Tim M. J. Ewoldt (Author), Alan Abdulla (Author), Wim J. R. Rietdijk (Author), Nelianne Verkaik (Author), Christian Ramakers (Author), Evelien de Jong (Author), Michael Osthoff (Author), Birgit C. P. Koch (Author), Henrik Endeman (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Model-informed precision dosing (MIPD) might be used to optimize antibiotic treatment. Procalcitonin (PCT) is a biomarker for severity of infection and response to antibiotic treatment. The aim of this study was to assess the impact of MIPD on the course of PCT and to investigate the association of...