Co-Spray Dried Nafamostat Mesylate with Lecithin and Mannitol as Respirable Microparticles for Targeted Pulmonary Delivery: Pharmacokinetics and Lung Distribution in Rats
Coronavirus disease 2019 (COVID-19), caused by a new strain of coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly worldwide. Nafamostat mesylate (NFM) suppresses transmembrane serine protease 2 and SARS-CoV-2 S protein-mediated fusion. In this study...
Saved in:
Main Authors: | Ji-Hyun Kang (Author), Young-Jin Kim (Author), Min-Seok Yang (Author), Dae Hwan Shin (Author), Dong-Wook Kim (Author), Il Yeong Park (Author), Chun-Woong Park (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2021-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
In vivo pharmacokinetic and pharmacodynamic study of co-spray-dried inhalable pirfenidone microparticles in rats
by: Ji-Hyun Kang, et al.
Published: (2022) -
The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation
by: Yong-Bin Kwon, et al.
Published: (2020) -
Design of respirable sprayed microparticles of encapsulated bacteriophages
by: Alberto Baldelli, et al.
Published: (2023) -
Encapsulation of Alcohol Dehydrogenase in Mannitol by Spray Drying
by: Hirokazu Shiga, et al.
Published: (2014) -
Development of Nafamostat Mesylate Immediate-Release Tablet by Drug Repositioning Using Quality-by-Design Approach
by: Hyeon-A Kim, et al.
Published: (2022)