Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice
The nucleotide second messenger 3', 5'-cyclic adenosine monophosphate (cAMP) and 3', 5'-cyclic guanosine monophosphate (cGMP) mediate fundamental functions of the brain, including learning and memory. Phosphodiesterase 3 (PDE3) can hydrolyze both cAMP and cGMP and appears to be i...
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Main Authors: | Shuichi Yanai (Author), Tetsuro Tago (Author), Jun Toyohara (Author), Tomoko Arasaki (Author), Shogo Endo (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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