Acute myelogenous leukemia - current recommendations and approaches in molecular-genetic assessment

Acute myelogenous leukemia is a multi-step hematological malignancy, affecting function, growth, proliferation and cell cycle of myeloid precursors. Overall assessment of patients with the disease requires among everything else, a comprehensive investigation of the genetic basis through various meth...

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Ngā kaituhi matua: Yahya Dinnar (Author), Hachmeriyan Mari (Author), Micheva Ilina (Author), Chervenkov Trifon (Author)
Hōputu: Pukapuka
I whakaputaina: Sciendo, 2022-06-01T00:00:00Z.
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Whakarāpopototanga:Acute myelogenous leukemia is a multi-step hematological malignancy, affecting function, growth, proliferation and cell cycle of myeloid precursors. Overall assessment of patients with the disease requires among everything else, a comprehensive investigation of the genetic basis through various methods such as cytogenetic and molecular-genetic ones. This clarification provides diagnostic refinement and carries prognostic and predictive value in respect of essential therapeutic choices.
Whakaahutanga tūemi:2501-062X
10.2478/rjim-2022-0004