The ameliorative effect of Primula vulgaris on cisplatin-induced nephrotoxicity in rats and quantification of its phenolic components using LC-ESI-MS/MS

• Hauptverfasser: Ibrahim Turan (VerfasserIn), Deniz Canbolat (VerfasserIn), Selim Demir (VerfasserIn), Gokcen Kerimoglu (VerfasserIn), Fatih Colak (VerfasserIn), Nihal Turkmen Alemdar (VerfasserIn), Ahmet Mentese (VerfasserIn), Yüksel Aliyazicioglu (VerfasserIn)
• Format: Buch
• Veröffentlicht: Elsevier, 2023-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Cisplatin (CDDP) is an important chemotherapeutic agent, accumulation of which in kidney tissue causes nephrotoxicity and renal failure. The aim of this study was to evaluate, for the first time in the literature, the protective effect of dimethyl sulfoxide (DMSO) extract of Primula vulgaris leaf (P...