Early identification of hERG liability in drug discovery programs by automated patch clamp
Blockade of the cardiac ion channel coded by hERG can lead to cardiac arrhythmia, which has become a major concern in drug discovery and development. Automated electrophysiological patch clamp allows assessment of hERG channel effects early in drug development to aid medicinal chemistry programs and...
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| Format: | Book |
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Frontiers Media S.A.,
2014-09-01T00:00:00Z.
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