Spectrophotometric Determination of Some Phenolic Compounds Using N,N- diethyl -p-phenylenediamine (DE - PPD) and Benzoyl peroxide
ABSTRACT<br /> A rapid and sensitive spectrophotometric method has been developed for the determination of some phenolic compounds (phenol, o-aminophenol and α-naphthol) and was applied for determination of amoxicillin drug. The method is based on oxidative coupling reaction of these compounds...
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| Main Authors: | , , |
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| Format: | Book |
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College of Education for Pure Sciences,
2013-08-01T00:00:00Z.
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| Summary: | ABSTRACT<br /> A rapid and sensitive spectrophotometric method has been developed for the determination of some phenolic compounds (phenol, o-aminophenol and α-naphthol) and was applied for determination of amoxicillin drug. The method is based on oxidative coupling reaction of these compounds with N,N-diethyl-p-phenylenediamine in the presence of benzoyl peroxide as oxidizing agent. The formed blue indophenol dyes have maximum absorptions at 627, 612.5, 611.5 and 628.5 nm. for phenol, o-aminophenol, α-naphthol and amoxicillin respectively. The molar absorptivities are 1.72× 104, 1.92× 104, 1.65 × 104. l. mol1-. cm-1 for concentrations obeyed Beer,s law in the ranges 0.2 -4.0, 0.5 -11.0, 0.6 - 16.0 and 0.8 - 25.0 µg ml-1 for the above compounds respectively. The average recovery % was ranged between 98.99% 100.45 with relative standard deviation ≤ 1.04 for all the studied compounds. The method is applied |
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| Item Description: | 1812-125X 2664-2530 10.33899/edusj.2013.89913 |