Interaction of some new 2-(substituted-thio)-quinazolin-4-ones with molybdenum hydroxylases: A pharmacophore prediction

Background: Molybdenum hydroxylases have been implicated as key oxidative enzymes in some diseases. Methods: Twenty 2-(substituted-thio)-quinazolin-4-one derivatives recently synthesized in our laboratory were examined for their inhibitory activity toward molybdenum hydroxylases. Results and conclus...

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Main Authors: Hussein I. El-Subbagh (Author), Alaa A.-M (Author), Mohamed A. Al-Omar (Author), Fatmah A. Al-Omary (Author)
Format: Book
Published: SpringerOpen, 2015-12-01T00:00:00Z.
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