Brain-derived neurotrophic factor in blood increases transiently after single sessions of moderate intensity exercise in obese females

• Main Authors: Slamet Raharjo (Author), Ahmad Syahru Mubarok Harisman (Author), Olivia Andiana (Author), Yualita Putri Pamungkas (Author)
• Format: Book
• Published: Universitas Nusantara PGRI Kediri, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

This study aimed to analyze the increase in serum BDNF levels after moderate-intensity exercise in obese females. This study used the True-Experimental method with the Randomized Control Group Pre-test-Post-test design. A total of 14 obese female adolescents aged 19-24 years participated in this study and were divided into two groups, i.e., the control group (CG, n=7) and the moderate-intensity exercise group (MIEG, n=7). The exercise was performed with an intensity of 64 - 76 HRmax for 40 minutes using a Richter Treadmill (4.0 HP DC). Moderate-intensity exercise was carried out in one intervention. Blood sampling was carried out before and after moderate-intensity exercise on the cubital vein as much as 3 ml. Examination of serum BDNF levels using the ELISA method.  The results of statistical analysis show that the mean pre-test serum BDNF levels were CG (258.66±27.11 pg/mL), MIEG (252.48±23.17 pg/mL), and (p=0.865). The mean post-test serum BDNF levels were CG (236.22±20.83 pg/mL), MIEG (497.73±59.55 pg/mL), and (p=0.001). The mean delta of serum BDNF levels on CG (-22.43±26.04), MIEG (245.25±61.57 pg/mL), and (p=0.002). Based on the study results, it is concluded that a single session of moderate-intensity exercise in the morning increases serum BDNF levels in obese females.

Item Description

2548-7833
2477-3379
10.29407/js_unpgri.v7i3.16372