COVID-19 cases and their outcome among patients with uncommon co-existing illnesses: A lesson from Northern India

• Үндсэн зохиолчид: D. Himanshu Reddy (Зохиогч), Virendra Atam (Зохиогч), Priyanka Rai (Зохиогч), Farman Khan (Зохиогч), Saurabh Pandey (Зохиогч), Hardeep Singh Malhotra (Зохиогч), Kamlesh Kumar Gupta (Зохиогч), Satyendra Kumar Sonkar (Зохиогч), Rajeev Verma (Зохиогч), Kauser Usman (Зохиогч), Shyam Chand Chaudhary (Зохиогч), Vivek Kumar (Зохиогч), Kamal Kumar Sawlani (Зохиогч), M.L. Patel (Зохиогч), D. Himanshu (Зохиогч), Ajay Kumar (Зохиогч), Sudhir Kr Verma (Зохиогч), Medhavi Gautam (Зохиогч), Harish Gupta (Зохиогч), Satish Kumar (Зохиогч), Deepak Baghchandanani (Зохиогч), Ambuj Yadav (Зохиогч), M. Lamba (Зохиогч), Amit Kumar (Зохиогч), Suhail (Зохиогч), Rati Prabha (Зохиогч), Darshan Bajaj (Зохиогч), Abhishek Bahadur Singh (Зохиогч), Mayank Mahendra (Зохиогч), Gaurav Kumar (Зохиогч), Narendra Kumar (Зохиогч), Bal Krishna Ojha (Зохиогч), Dhananjay Kumar Verma (Зохиогч), Vinod Kumar (Зохиогч), Suresh Singh (Зохиогч), Shivam Gupta (Зохиогч), Mohammad Hashim (Зохиогч), Kuldeep Verma (Зохиогч), Akriti Bhardwaj (Зохиогч), Anurag Chaudhary (Зохиогч), Himanshu Chaudhan (Зохиогч), Kaustubh (Зохиогч), Kinjalk Dubey (Зохиогч), Naveen Kumar (Зохиогч), Rituraj (Зохиогч), Janmajay Kumar (Зохиогч), Somesh Srivastav (Зохиогч), Shiv Paratap Singh (Зохиогч), Sunita Kumari (Зохиогч), Sudham Srivastave (Зохиогч), Jyoti Verma (Зохиогч), Mohmmad Ahmad Hussain (Зохиогч), Ammar Sabir Siddiqui (Зохиогч), Azher Rizvi (Зохиогч), Chitranshu Pancholi (Зохиогч), Deepak Sharma (Зохиогч), Deepak Kumar Verma (Зохиогч), David Zothansanga (Зохиогч), Kuldeep Singh (Зохиогч), Prashant Kumar Singh (Зохиогч), Rahul Kumar (Зохиогч), Vipin Raj Bharti (Зохиогч), Shahnawaz Ali Ansari (Зохиогч), Monika Kallani (Зохиогч), Harish Bharti (Зохиогч), Ankita Singh (Зохиогч), Avirup Majumdar (Зохиогч), Neeraj Verma (Зохиогч), Mayank Mishra (Зохиогч), Pankaj Kumar Gupta (Зохиогч), Shubhanshu Shivhare (Зохиогч), Mudit Kotwal (Зохиогч), Prashant Mahar (Зохиогч), Praduman Mall (Зохиогч), Krishnapal Singh Parmar (Зохиогч), Guddoo Kumar (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2022-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Тойм

Introduction: Newer coexisting conditions should be identified in order to modify newer risk factors. Aim was to identify patients with non-classical or less common coexisting conditions in patients infected of COVID 19. Method: Single centred study from June 2020 to May 2021 at a tertiary centre in North India. A preformed questionnaire was used to record clinical and laboratory parameters and to identify cases which are in addition to CDC list and Indian data. Results: 0.67% (46) cases out of 6832 patients were identified to have non-classical coexisting illness. It was divided into 2 groups-infections A (60.1%) and non-infections B (39.9%). Group A included-tuberculosis- pulmonary (14.3%) & extra pulmonary (32.9%), bacterial (25.0%) viral infections [dengue, hepatitis B & C] (14.3%), HIV disease (10.7%) and malaria (3.6%). Group B included- organ transplant (27.8%), autoimmune [myasthenia gravis, polymyositis, psoriasis] (22.6%), haematologic [Haemophilia, ITP, Aplastic anaemia, APML, CML] (27.8%), uncommon malignancies [disseminated sacral chordoma and GTN] (11.1%) and snakebite (11.1%). Serum Procalcitonin was not helpful for diagnosis of bacterial infection in COVID-19 disease. Group A had significantly longer duration of illness, hepatitis and elevated CRP. The mortality in group A & B were 32.1% and 43.8% respectively. Death in non-severe COVID cases was in tetanus and snakebite. 30.7% death among tuberculosis patients. More than 70% of deaths were attributable to COVID 19 in both the groups. Conclusion: In Indian settings, comorbidities like tuberculosis and bacterial infections can precipitate severe COVID 19 unlike other parts of the world where tuberculosis is relatively uncommon.

Зүйлийн тодорхойлолт

2213-3984
10.1016/j.cegh.2022.101044