Exploring the kinetic selectivity of drugs targeting the β1‐adrenoceptor
Abstract In this study, we report the β1‐adrenoceptor binding kinetics of several clinically relevant β1/2‐adrenoceptor (β1/2AR) agonists and antagonists. [3H]‐DHA was used to label CHO‐β1AR for binding studies. The kinetics of ligand binding was assessed using a competition association binding meth...
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Main Authors: | David A. Sykes (Author), Mireia Jiménez‐Rosés (Author), John Reilly (Author), Robin A. Fairhurst (Author), Steven J. Charlton (Author), Dmitry B. Veprintsev (Author) |
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Format: | Book |
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Wiley,
2022-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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