The Prophylaxis of Febrile Convulsions in Childhood: Secular Trends in the Last Decade (2007-2008 versus 2017-2018)

Aim:To analyze trends in the prophylaxis of febrile convulsions (FC) in childhood by comparing two cohorts from the previous two decades (2007-2008 versus 2017-2018).Materials and Methods:The cohort consisted of 272 children with FC who were followed up during the 2007-2008 (n=105) and 2017-2018 (n=...

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Main Authors: Seda Kanmaz (Author), Yavuz Ataş (Author), Dilara Ece Toprak (Author), Elif Hoşcoşkun (Author), Cemile Büşra Ölçülü (Author), Tuğçe İnce (Author), Özlem Yılmaz (Author), Gürsel Şen (Author), Sanem Yılmaz (Author), Hasan Tekgül (Author)
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Published: Galenos Yayinevi, 2023-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Seda Kanmaz  |e author 
700 1 0 |a Yavuz Ataş  |e author 
700 1 0 |a Dilara Ece Toprak  |e author 
700 1 0 |a Elif Hoşcoşkun  |e author 
700 1 0 |a Cemile Büşra Ölçülü  |e author 
700 1 0 |a Tuğçe İnce  |e author 
700 1 0 |a Özlem Yılmaz  |e author 
700 1 0 |a Gürsel Şen  |e author 
700 1 0 |a Sanem Yılmaz  |e author 
700 1 0 |a Hasan Tekgül  |e author 
245 0 0 |a The Prophylaxis of Febrile Convulsions in Childhood: Secular Trends in the Last Decade (2007-2008 versus 2017-2018) 
260 |b Galenos Yayinevi,   |c 2023-03-01T00:00:00Z. 
500 |a 2147-9445 
500 |a 2587-2478 
500 |a 10.4274/jpr.galenos.2022.87847 
520 |a Aim:To analyze trends in the prophylaxis of febrile convulsions (FC) in childhood by comparing two cohorts from the previous two decades (2007-2008 versus 2017-2018).Materials and Methods:The cohort consisted of 272 children with FC who were followed up during the 2007-2008 (n=105) and 2017-2018 (n=167) periods in Ege University Faculty of Medicine Children's Hospital. The following clinical parameters were analyzed: demographic data, FC types, prophylaxis types, selected anti-seizure medications (ASM), recurrence risk factors, and electroencephalography (EEG) characteristics.Results:We defined two secular trends for the prophylaxis of FC in children in the last decade: (1) a reduced rate of FC prophylaxis (22.1%) in the period of 2017-2018 compared with a rate of 63.8% in 2007-2008, p<0.01, (2) no impact of recurrence risk factors for the initiation of prophylaxis for complex FC in the last decade (p=0.028). The mean number of previous seizures at the initiation of the ASM prophylaxis increased from 2.8±1.13 to 3.4±2.00 for simple FC and from 1.9±0.24 to 3.1±0.31 for complex FC (p<0.01) in the period of 2017-2018.Conclusion:Prophylaxis rates were determined to be lower in the last decade in children with FC. There was no impact of recurrence risk factors for the initiation of prophylaxis in children with simple or complex FC. 
546 |a EN 
546 |a TR 
690 |a febrile convulsion 
690 |a asm prophylaxis 
690 |a febrile convulsion recurrence risk factors 
690 |a Medicine 
690 |a R 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Journal of Pediatric Research, Vol 10, Iss 1, Pp 19-25 (2023) 
787 0 |n  http://jpedres.org/archives/archive-detail/article-preview/the-prophylaxis-of-febrile-convulsions-in-childhoo/58765  
787 0 |n https://doaj.org/toc/2147-9445 
787 0 |n https://doaj.org/toc/2587-2478 
856 4 1 |u https://doaj.org/article/23a29ef76f9f430798018cf59c62fbd8  |z Connect to this object online.