Comparative Analysis of Hematological and Biochemical Changes in Neonates among Women with and without COVID-19 Infection during Pregnancy

• Main Authors: Daniela-Eugenia Popescu (Author), Simona Cerbu (Author), Ioana Rosca (Author), Nicoleta Lungu (Author), Ana Adriana Trușculescu (Author), Valerica Belengeanu (Author), Aniko Maria Manea (Author), Mirabela Adina Dima (Author), Florin Gorun (Author), Zoran Laurentiu Popa (Author), Doru Ciprian Crisan (Author), Marioara Boia (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 10.3390/children10081370; 2227-9067
• Keywords: COVID-19; vertical transmission; pregnancy complications; Pediatrics; RJ1-570
• Source: Children, Vol 10, Iss 8, p 1370 (2023)

The aim of this study is to evaluate the test results of neonates delivered by COVID-19-positive mothers during pregnancy with those of neonates born to unvaccinated mothers who are COVID-19-free. A cohort study was conducted on 367 pregnant women who gave birth at Premiere Hospital, Timisoara, Romania, between May 2021 and February 2022. Two groups were established: Group 1, with 167 pregnant women infected with COVID-19, and Group 2, with 200 pregnant women who were not affected by COVID-19 during pregnancy. Maternal laboratory examination did not exhibit significant variations except for platelet count. In neonatal blood tests, WBC had a significantly lower median value in the group born to COVID-19-free mothers. Neonatal anemia and leukocytosis showed slightly higher prevalence in Group 1, but the differences were not statistically significant. This study suggests that maternal COVID-19 infection during pregnancy does not have significant associations with most maternal and neonatal characteristics.