A high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP-43A315T mutant C57BL6/J mice

• Auteurs principaux: Karen S. Coughlan (Auteur), Luise Halang (Auteur), Ina Woods (Auteur), Jochen H. M. Prehn (Auteur)
• Format: Livre
• Publié: The Company of Biologists, 2016-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Transgenic transactivation response DNA-binding protein 43 (TDP-43) mice expressing the A315T mutation under control of the murine prion promoter progressively develop motor function deficits and are considered a new model for the study of amyotrophic lateral sclerosis (ALS); however, premature sudd...